Management of Prelabor Rupture of the Membranes at Term

• Status: Not yet recruiting
• Trial end date: 2023-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

Prolonged rupture of membranes has been associated with increased risk of chorioamnionitis and endometritis. In this study the investigators will investigate whether an early intervention to augment labor with oxytocin is superior to expected management for spontaneous delivery (up to 24 hours).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rambam Health Care Campus
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

1. Primiparous women with a singleton pregnancy that are admitted with prelabor rupture of membranes.

2. Women at gestational age 370/7 or more.

3. Vertex presentation.

Exclusion Criteria:

1. Age 18 and under.

2. High order gestation.

3. Women with contraindication for a vaginal delivery.

4. Active labor.

5. Documented fetal anomalies.

6. Known or suspected intrauterine infection (temperature > 38 degrees, leucocytosis).

7. Non reassuring fetal heart rate tracing.

8. Positive group B streptococcus status.