Management of Postoperative Pain After Total Knee Replacement.

• Status: Completed
• Trial end date: 2013-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare two methods of postoperative pain management in patients undergoing total knee replacement.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mark J. Spangehl, M.D.
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

• Unilateral primary total knee replacement.

• Weight 50-125 kg.

• Age 18-79 years.

• Intact neurological exam to the surgical lower extremity.

• Cognitively intact with ability to sign informed consent.

Exclusion Criteria:

• Renal insufficiency with creatinine >1.5 mg/dL.

• Allergy to medication used in the study.

• Using narcotic medication prior to surgery (morphine equivalents >=20 mg/day for >7 days.)

• Prior open knee surgery with regional anesthesia or periarticular injection for post-operative pain management.