Management of Myocardial Injury After Noncardiac Surgery Trial
Status:
Completed
Trial end date:
2018-03-01
Target enrollment:
Participant gender:
Summary
Patients who have myocardial injury after noncardiac surgery are at a higher risk of dying
than those who do not. One in 10 patients with myocardial injury will die within 30 days of
surgery. This risk of death exists up to one year after myocardial injury. There are
currently no treatments or guidelines available for heart injury after surgery, but there is
evidence that taking a blood-thinner can prevent some of the deaths, both in the short and
long-term. The purpose of this trial is to test the effect of two drugs (dabigatran and
omeprazole) that may prevent mortality, major cardiovascular complications and major upper
gastrointestinal bleeding in patients who have had myocardial injury after noncardiac
surgery.