Management of Acute Pulmonary Hypertensive Crisis in Children With Known Pulmonary Arterial Hypertension
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Pulmonary arterial hypertension (PAH) is a disease where the blood pressure in the pulmonary
arteries (PAP) is high. PAH increases the risk of adverse events, including death, during and
or after procedures. The severity of baseline PAH correlates with the incidence of major
complications, such that those with PAP higher than their systemic blood pressure (SBP) had a
8 fold increased risk of complications. These children present for procedures where an acute
exacerbation of their chronic illness-termed Pulmonary Hypertensive (PH)crisis, can occur,
often resulting in death if not detected and managed expeditiously. Unfortunately there is
little data and no consensus in the pediatric literature on how PH crisis should be managed.
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