Magnesium Sulphate for Attenuation of Hemodynamic Pressor Response After Myfield's Clamp Application

• Status: Completed
• Trial end date: 2017-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Use of Mayfield skull clamp during craniotomies; results in a sharp and intense noxious stimulus which results in a severe hemodynamic pressor response. Many strategies have been reported to blunt this undesirable pressor effect. This prospective, double blind, and randomized study is the first to evaluate the effect of MgSo4 on attenuation of hemodynamic pressor activity after head clamp application during craniotomies.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: El-Sahel Teaching Hospital
• Treatments: Anesthetics; Magnesium Sulfate

Criteria

Inclusion Criteria:

• All adult patients aged from 18 to 60 years

• of both genders

• ASA physical status I and II

• scheduled for craniotomies

Exclusion Criteria:

• history of MgSo4 consumption or allergy

• renal disease

• hepatic or endocrine disorder

• cardiovascular dysfunction

• calcium channel blocker intake

• drug abuse were excluded from this study.