Magnesium Sulphate Versus Ketamine as an Adjuvant to Bupivacaine in Pectoral Nerve Block During Mastectomy

• Status: Not yet recruiting
• Trial end date: 2023-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

There are no published article that compare magnesium sulfate and ketamine as adjuvants to bupivacaine in PECS block , so the aim of this study is to evaluate the efficacy of Magnesium sulfate versus ketamine when added to local anesthetic ( Bupivacaine) in pectoral nerve block during mastectomy and detect which of these drugs has the more effective analgesic effect and decrease opioid consumption .

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beni-Suef University
• Treatments: Bupivacaine; Ketamine; Magnesium Sulfate

Criteria

Inclusion Criteria:

• Female patient

• Age from 30 to 70 years old

• American Society of Anesthesiologists (ASA) I-II

Exclusion Criteria:

• Cognitive impairment

• History of alcohol or drug abuse

• Allergy to the studied drugs

• Patients with coagulation disorders

• Block site infection

• Uncontrolled diabetes mellitus

• Uncontrolled hypertension

• Body Mass Index( BMI) more than 30 kg/m2