Overview
Magnesium Sulphate, Dexemeditomedine and Emergency Agitation
Status:
Recruiting
Recruiting
Trial end date:
2020-09-01
2020-09-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Emergence agitation is a postanesthetic phenomenon that develops in the early phase of general anesthesia recovery, and is characterized by agitation, confusion, disorientation, and possible violent behavior. Though agitation is observed more frequently in pediatric patients, the incidence in adults has been reported at 4.7% or 21.3%. Emergence agitation can lead to serious consequences such as self-extubation, removal of catheters, hemorrhage, and even severe injuries from falling out of the bed. Furthermore, it may increase the demand on human resources and cause medical staff injuries.Phase:
Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
South Valley UniversityTreatments:
Dexmedetomidine
Criteria
Inclusion Criteria:- Both genders
- Aged 20-40 years.
- With American Society of Anesthesiologists (ASA) physical status I or II.
- Nonsmokers.
- BMI less than or equal to 30.
- Elective nasal surgery under general anesthesia in which nasal packing on each side
was used postoperatively.
Exclusion Criteria:
- Patients with history of uncontrolled hypertension.
- Patients with ischemic or valvular heart disease.
- Patients use MAO inhibitors or adrenergic block.
- Cognitive impairment.
- Patients taking antipsychotics.
- Renal insufficiency or liver impairment.