Magnesium Sulfate to Prevent Hospitalisation of Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Status:
Withdrawn
Trial end date:
2017-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to assess whether administration of a bolus dose of MgSO4
(magnesium sulfate) plus standard therapy is superior to standard therapy alone for the
management of Acute Exacerbations of Chronic Pulmonary Obstructive Disease (AECOPD) in the
emergency department. The investigators hypothesize that MgSO4 causes faster recovery of the
bronchospasm, and a reduction of the dead space, translating to the following clinical
outcomes : less hospitalisation, lower length of stay (LOS), better composite outcome of
hospitalisation + LOS + readmission for AECOPD.