Magnesium Sulfate During the Postpartum in Women With Severe Preeclampsia

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

There is no evidence that patients receiving magnesium sulfate before birth are required to maintain the drug for 24 hours. Therefore the investigators will have a randomized clinical study in patients with severe preeclampsia who have been treated with impregnation of magnesium sulphate and at least eight hours have received the drug before birth. If the patient agrees and signs the consent is randomized to: 1-receive sulfate for 24 hours postpartum as usual or, 2- not receiving the postpartum magnesium sulfate or other anticonvulsant drugs. This study can be conducted in 12 maternity latin america.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Complejo Hospitalario Dr. Arnulfo Arias Madrid
• Treatments: Magnesium Sulfate

Criteria

Inclusion Criteria:

• Severe preeclampsia or severe preeclampsia aggregated to chronic hypertension with > 24 weeks of gestation treated with 4-6 grams of magnesium sulfate for impregnation with a minimum of 8 hours continuous of magnesium sulfate before delivery

• The study begins to terminate pregnancy

Exclusion Criteria:

• HELLP syndrome

• Eclampsia

• Renal insufficiency

• Diabetes mellitus

• Disease of collagen

• Heart disease