Overview

Magnesium Oral Supplementation to Reduce Pain Inpatients With Severe Peripheral Arterial Occlusive Disease

Status:
Unknown status
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
Magnesium exerts analgesic effects in several animal pain models and in patients affected by acute postoperative pain and chronic pain of neuropathic origin. There is no evidence that magnesium can modulate pain in patients with peripheral arterial occlusive disease (PAOD). We describe the protocol of a single-center randomized double-blind clinical trial aimed at assessing the efficacy of oral magnesium supplementation in controlling severe pain in patients with advanced PAOD.
Phase:
N/A
Details
Lead Sponsor:
Azienda Ospedaliera Spedali Civili di Brescia
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Treatments:
Magnesium Oxide
Oxycodone
Pregabalin