MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Phase I trial to study the effectiveness of combining MS-275 with isotretinoin in treating
patients who have metastatic or advanced solid tumors or lymphomas. MS-275 may stop the
growth of cancer cells by blocking the enzymes necessary for their growth. Isotretinoin may
help cancer cells develop into normal cells. MS-275 may increase the effectiveness of
isotretinoin by making cancer cells more sensitive to the drug. MS-275 and isotretinoin may
also stop the growth of solid tumors or lymphomas by stopping blood flow to the cancer.
Combining MS-275 with isotretinoin may kill more cancer cells