MORphine Use in the Fascia Iliaca Compartment Block With UltraSound
Status:
Terminated
Trial end date:
2020-02-18
Target enrollment:
Participant gender:
Summary
Appropriate management of analgesia for proximal femoral fractures is a common problem in the
emergency department (ED). Side effects from morphine usage such as nausea, vomiting,
respiratory depression, sedation, and obstipation are especially pronounced in elderly.
Fascia Iliaca Compartment Block (FICB) holds promise as a simple and safe, and effective
alternative method to reduce pain. Local anaesthetic injected in the anatomic space
underlying the fascia iliaca, spreads to block the nerves traversing it. This regional
anaesthesia includes the femoral nerve. Previous studies in the ED showed promise but lacked
blinding, involved low numbers of subjects, or did not use ultrasound localisation of the
injection site. The latter is becoming common practice. In this randomised placebo controlled
trial the FICB with ultrasound localisation of injection of levobupivacaïne will be compared
to the FICB with placebo. It aims to prove that less morphine is used in the intervention
group. Other research parameters are pain scores and minor adverse events related to morphine
use.