Overview

MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function

Status:
Withdrawn
Trial end date:
2025-07-01
Target enrollment:
Participant gender:
Summary
This study is for patients with cirrhosis and hepatic encephalopathy who are in the hospital. This means they have a high ammonia level which is affecting their brain function. All patients will receive the standard of (regular) care. Each will have an equal chance (like flipping a coin) of receiving the experimental drug or placebo along with the standard care. Each patient will have tests during the first 24 hours, receive treatment for up to 5 days, and have 30 days of follow-up.
Phase:
Phase 3
Details
Lead Sponsor:
Mallinckrodt
Treatments:
Phenylacetic acid