It is important to predict the influence of the neuromuscular blocking agents on the motor
evoked potential. Investigator will investigate the dose-response relationship between the
degree of the neuromuscular blockade and the motor evoked potential in patients undergoing
brain tumor surgery using the population approach. Investigator will investigate the
influence of the other factors such as the impedence, reactance, muscel amount, and age on
the motor evoked potential.