Lung Nodule Detection Using Ultra-long FOV PET/CT

• Status: Recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Indeterminate lung nodules (6-15mm) are frequent findings in patients undergoing chest CT scanning, but adequate follow-up imaging is currently not in place to facilitate early detection, diagnosis and decision making regarding treatment.

The introduction of long Field-Of-View PET/CT scanners could make a difference in this matter due to the substantial increase in sensitivity allowing optimal image quality. Whether this new technology could provide improved detection and follow-up of indeterminate lung nodules is what we aim to explore in this study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Medical Center Groningen
• Treatments: Fluorodeoxyglucose F18

Criteria

Inclusion Criteria:

• able to give informed consent

• signed informed consent

• confirmed indeterminate lung nodule(s) of 6-15 mm in size on CT chest imaging

• routine 18F-FDG PET/CT performed

• scheduled for biopsy or resection of the lung nodules

Exclusion Criteria:

• claustrophobia

• pregnant or breastfeeding

• interval of at least 2 weeks between PET scan and last date of systemic anti-cancer therapy to reduce false-negative uptake in lesions

• radiation therapy of the target lung nodule(s)

• uncontrolled diabetes mellitus

• any medical condition potentially hampering conduction of the trial