Lung Deposition of the BDP/Formoterol Combination Administered Via the NEXT DPI in Healthy, Asthmatic and COPD Patients
Status:
Completed
Trial end date:
2010-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate the lung deposition and distribution pattern of
Beclometasone and Formoterol using a gamma-scintigraphic technique after inhalation of a
single dose of 99mTc-radiolabelled BDP/formoterol fixed combination administered Via the NEXT
DPI in healthy volunteers, asthmatic and COPD patients. Additionally, the systemic exposures
to formoterol, BDP and its monopropionate metabolite (B17MP) will be investigated.