Lumigan Versus Cosopt

• Status: Completed
• Trial end date: 2007-05-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare the intraocular pressure effect and safety of the dorzolamide/timolol fixed combination given twice daily versus bimatoprost given once every evening in patients with open-angle glaucoma in patients insufficiently controlled on latanoprost monotherapy

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pharmaceutical Research Network
• Treatments: Bimatoprost; Dorzolamide; Timolol

Criteria

Inclusion Criteria:

• adults with a diagnosis of bilateral open-angle glaucoma including: primary, pigment dispersion or exfoliation in both eyes

• on no therapy the intraocular pressure should be 22-29 mm Hg inclusive at the 8:00 AM measurement

• visual acuity should be 20/200 or better in each eye

Exclusion Criteria:

• historical failure to respond to topical beta-blockers in a clinically meaningful manner

• any contraindication to study medications

• any anticipated change, or modification in the 6 weeks prior to Visit 1, in systemic hypertensive therapy during the trial