Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

• Status: Not yet recruiting
• Trial end date: 2024-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital for Special Surgery, New York
• Treatments: Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate

Criteria

Inclusion Criteria:

• Patients scheduled to undergo 1 to 2 level laminectomy

• Between the ages of 18-85

Exclusion Criteria:

• Minimally invasive surgery

• Prior daily opioid usage within 6 months.

• Use of concomitant procedures such as spinal fusion, revision procedure at the same level.

• History of a chronic pain syndrome, uncontrolled diabetes defined as A1C > 6.5, immunocompromised condition such as active cancer treatment, history of transplant, benign prostatic hyperplasia or history of urinary retention, and other conditions which require chronic steroid therapy or immunosuppressants.

• Non-English speakers

• Patients allergic to Depo-Medrol and/or glucocorticoids, or other steroids