Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients
Status:
Recruiting
Trial end date:
2022-04-10
Target enrollment:
Participant gender:
Summary
Postoperative delirium（POD）is a common complication that can directly affect important
clinical outcomes, and exert an enormous burden on patients, their families, hospitals, and
public resources. In order to evaluate whether an intraoperative administration of low-dose
neuroleptanalgesia reduces postoperative delirium, droperidol 1.25 mg and fentanyl 0.025 mg
or normal saline is used by intravenous injection 30 minutes before the end of the operation,
in elderly patients with non-cardiac major surgery under general anesthesia. The efficiency
and safety of neuroleptanalgesia on the incidence of POD would be evaluated in elderly
patients.