Overview

Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI)

Status:
Completed
Trial end date:
2019-06-06
Target enrollment:
Participant gender:
Summary
To assess the overall safety and efficacy of intra-arterial (IA) bevacizumab for the treatment of radiation necrosis. A single 2.5 mg/kg dose of bevacizumab will be given intra-arterially after osmotic blood-brain-barrier disruption.
Phase:
Phase 2
Details
Lead Sponsor:
Norton Healthcare
Collaborator:
University of Kentucky
Treatments:
Bevacizumab
Mannitol