Low-dose GH Supplementation Increases Clinical Pregnancy Rate

• Status: Completed
• Trial end date: 2017-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The objective of this study is to assess whether a low dose of GH supplementation (0.5 IU/day) increases clinical pregnancy rates in women with a history of POR who failed to become pregnant in two previous IVF cycles.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centro de Infertilidad y Reproducción Humana
• Treatments: Hormones

Criteria

Inclusion Criteria:

• Women with a history of POR, defined according to the Bologna criteria

• Absence of pregnancy in at least two previous IVF cycles

Exclusion Criteria:

• Body mass index ≥ 30 kg/m2

• Presence of endocrinopathies

• Altered karyotype in one or both partners

• History of invasive ovarian surgery

• History of chronic, autoimmune or metabolic diseases

• Altered meiosis in testicular biopsy or altered sperm-FISH

• Drug therapy in the male partner

• Participation, within the previous 6 months, in another clinical trial with medication