Low INR to Minimize Bleeding With Mechanical Valves Trial
Status:
Recruiting
Trial end date:
2022-09-01
Target enrollment:
Participant gender:
Summary
This study evaluates the use of a lower INR target (1.5 to 2.5) in patients with a mechanical
heart valve in the aortic position. This study will inform physicians about whether a lower
INR target will decrease the risk of bleeding or increase the risk of blood clot formation
and stroke. These results have the potential to reduce the burden of bleeding in patients
with a mechanical heart valve who require lifelong warfarin (Coumadin) treatment.
Phase:
Phase 3
Details
Lead Sponsor:
McMaster University Population Health Research Institute