Low Exhaled NO and ICS in Suspected Asthma

• Status: Unknown status
• Trial end date: 2018-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether a low exhaled nitric oxide reading (<27ppb) is a good predictor of a negative response to inhaled steroid treatment for patients with symptoms suggestive of asthma.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Nottingham
• Treatments: Budesonide

Criteria

Inclusion Criteria:

1. Aged 18 years or over.

2. Asthma suspected by GP/Practice Nurse

3. Must be able to give informed consent

4. Exhaled Nitric Oxide reading <27ppb

5. FEV1 >70% predicted

Exclusion Criteria:

1. Patients requiring oral steroid treatment on visit to GP/Practice nurse

2. Use of oral prednisolone or antibiotics within last 4 weeks

3. Already using an inhaled corticosteroid

4. Any other clinically significant co-morbidity.

5. Expectant or breast feeding mothers.