Low Doses of Cholestyramine in the Treatment of Hyperthyroidism
Status:
Completed
Trial end date:
2008-01-01
Target enrollment:
Participant gender:
Summary
The enterohepatic circulation of thyroid hormones is increased in thyrotoxicosis.Bile-salt
sequestrants (ionic exchange resins) bind thyroid hormones in the intestine and thereby
increase their fecal excretion. Based on these observations, the use of cholestyramine has
been tried. The present study evaluates the effect of low doses of cholestyramine as an
adjunctive therapy in the management of hyperthyroidism