Low Doses of Cholestyramine in the Treatment of Hyperthyroidism

• Status: Completed
• Trial end date: 2008-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The enterohepatic circulation of thyroid hormones is increased in thyrotoxicosis.Bile-salt sequestrants (ionic exchange resins) bind thyroid hormones in the intestine and thereby increase their fecal excretion. Based on these observations, the use of cholestyramine has been tried. The present study evaluates the effect of low doses of cholestyramine as an adjunctive therapy in the management of hyperthyroidism

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shiraz University of Medical Sciences
• Treatments: Cholestyramine Resin

Criteria

Inclusion Criteria:

• Patients with newly diagnosed hyperthyroid Graves' disease

Exclusion Criteria:

• If the patient had been treated previously

• diabetes, kidney, or liver disease