Low-Dose Versus High-Dose Oxytocin Dosing for Induction and Augmentation of Labor
Status:
Not yet recruiting
Trial end date:
2026-04-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare oxytocin infusion rates for induction and
augmentation of labor in nulliparous women. The main question[s] it aims to answer are:
- Does a high dose oxytocin infusion protocol affect length of induction to delivery
interval?
- Does a high dose oxytocin infusion protocol affect mode of delivery?
- Does a high dose oxytocin infusion protocol affect maternal and neonatal outcomes?
Participants will be randomized to either low- or high-dose oxytocin groups:
- The low dose group will receive an infusion to start at 2 milli-units/min and will be
increased by 2 milli-units/min every 20 minutes. The maximum rate of infusion is 40
milli-units/min.
- The high dose group will receive an infusion to start at 6 milli-units/min and will be
increased by 6 milli-units/min every 20 minutes. Maximum rate of infusion is 40
milli-units/min.