Overview

Low Dose Metronomic Poly-chemotherapy for Metastatic CRC

Status:
Completed
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
This study investigates the activity of a new regimen of treatment for patients with metastatic colorectal carcinoma. This includes a combination of well-known chemotherapy agents and anti-inflammatory agents, when administered orally at low daily doses and without planed brakes (Low Dose Metronomic regimen), in contrast with the conventional and already exhausted regimens of treatment at Maximal Tolerated Doses (MTD) which required pre-planned brakes between treatment days.
Phase:
Phase 2
Details
Lead Sponsor:
HaEmek Medical Center, Israel
Treatments:
Capecitabine
Celecoxib
Cyclophosphamide
Methotrexate