Overview

Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction

Status:
Completed

Trial end date:
2019-12-01

Target enrollment:

Participant gender:

Summary

The purpose of the study is to determine if low doses of BNP can improve renal function in people with chronic heart failure with renal dysfunction, also to determine whether Sildenafil assists with improvement. This study will enroll only hospitalized patients with heart failure.

Phase:

Phase 1/Phase 2

Details

Lead Sponsor:

Mayo Clinic

Collaborator:

National Institutes of Health (NIH)

Treatments:

Natriuretic Peptide, Brain