Overview

Low Dose Aprepitant for Patients Receiving Carboplatin

Status:
Recruiting
Trial end date:
2021-08-30
Target enrollment:
Participant gender:
Summary
This study evaluates a simple one day prophylaxis of nausea and vomiting for patients who are getting carboplatin based chemotherapy. In addition to standard oral dexmethasone and oral ondansetrone, participants will be given a third neurokinin 1 (NK1) antagonist agent, either Aprepitant or Fosaprepitant (they have been shown to be equally effective) to improve prevention of nausea and vomiting. No medications need to be taken beyond day 1.
Phase:
Phase 2
Details
Lead Sponsor:
Albert Einstein College of Medicine
Albert Einstein College of Medicine, Inc.
Collaborator:
Jacobi Medical Center
Treatments:
Antiemetics
Aprepitant
BB 1101
Carboplatin
Dexamethasone
Dexamethasone acetate
Fosaprepitant
Ondansetron