Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy Volunteers

• Status: Completed
• Trial end date: 2011-05-17
• Target enrollment: 0
• Participant gender: All

Summary

RATIONALE: Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting.PURPOSE: This clinical trial studies lorazepam, diphenhydramine hydrochloride, and haloperidol gel in healthy volunteers.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Virginia Commonwealth University
• Collaborators: American Cancer Society, Inc.; National Cancer Institute (NCI)
• Treatments: Diphenhydramine; Haloperidol; Haloperidol decanoate; Lorazepam; Promethazine

Criteria

Inclusion Criteria:

• Completed a medical screening questionnaire

• English speaking

• No allergies to the drugs

• Able to complete the forms

• If a woman of childbearing age, agree to use contraception

Exclusion Criteria:

• History of substance abuse, psychiatric disorder, acquired brain injury, the possibility of pregnancy (not using birth control, and of child bearing age)

• Use of any medication that would contraindicate benzodiazepine administration

• Pregnant or nursing