Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study
Status:
Terminated
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
Clinical experience show limited effect of the drug Loperamide used to decrease output in
stoma patients. Therefore the investigators see the need for a randomized blinded clinical
trial to determine the effect of Loperamide opposite Placebo.
Loperamide will be evaluated in relation to the following parameters
- Change in ileostomy output in g/day in relation to oral intake
- Quantification of the change in intestinal transit time using a radiopaque marker
- The patient´s own assessment on which period they received Loperamide or Placebo