Longitudinal Study on the Neuroprotective and Neurotrophic Effects of Lithium
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
Thirty subjects with a DSM-IV (Diagnostic and Statistical Manual, fourth version)diagnosis of
BPD during a depressive or hypomanic episode will be divided in two groups according to age
and time of illness. All patients will receive lithium (flexible therapeutic dose) for 6
weeks and improvement will be evaluated weekly using depression and mania rating scales; this
study also objectives to identify state/trait markers and predictors of response.