Long-term Effectiveness of the Antiobesity Medication Phentermine
Status:
Not yet recruiting
Trial end date:
2025-09-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to understand the long-term effects of the drug
phentermine on weight, blood pressure, other health outcomes, and safety. Phentermine has
been approved by the US Food and Drug Administration (FDA) for weight management since 1959,
but it has not been approved for long-term use (i.e., treatment lasting more than 12 weeks).
This trial is designed to learn about the long-term effects of phentermine for up to 2 years
because obesity is a chronic disease and expert guidelines recommend long-term use of
anti-obesity medications as one treatment option.
Phase:
Phase 4
Details
Lead Sponsor:
Wake Forest University Health Sciences
Collaborators:
Biomedical Research Institute of New Mexico HealthPartners Institute Johns Hopkins University Kaiser Permanente KVK-Tech, Inc. National Heart, Lung, and Blood Institute (NHLBI) The University of Texas Health Science Center, Houston WW International Inc.