Overview

Long-term Beta-blocker Therapy After Acute Myocardial Infarction

Status:
Not yet recruiting
Trial end date:
2026-03-20
Target enrollment:
Participant gender:
Summary
The aim of the study is to determine whether discontinuation of β-blocker after at least 1 year of β-blocker therapy is noninferior to continuation of β-blocker in patients without heart failure (HF) or left ventricular systolic dysfunction after acute myocardial infarction (AMI). Prospective, open-label, randomized, multicenter, noninferiority trial to determine whether discontinuation of β-blocker after at least 1 year of β-blocker therapy is noninferior to continuation of β-blocker in patients without HF or left ventricular systolic dysfunction after AMI.
Phase:
Phase 4
Details
Lead Sponsor:
Samsung Medical Center
Collaborators:
Chonbuk National University Hospital
Chonnam National University Hospital
Chosun University Hospital
Chungbuk National University Hospital
Chungnam National University Hospital
Ewha Womans University
Ewha Womans University Seoul Hospital
Gyeongsang National University Hospital
Inje University
Jeju National University Hospital
Kangbuk Samsung Hospital
Keimyung University Dongsan Medical Center
Korea University Anam Hospital
Kyung Hee University Hospital
Presbyterian medical center
Saint Vincent's Hospital, Korea
Samsung Changwon Hospital
Sejong General Hospital
Seoul National University Bundang Hospital
Wonju Severance Christian Hospital
Wonkwang University Hospital
Treatments:
Adrenergic beta-Antagonists