Long Term Postoperative Cognitive Dysfunction in the Elderly Patients

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purposes of this study are to determine whether long-term postoperative cognitive dysfunction (POCD) is occured after general anesthesia and anesthetic drugs have an effect on the result about POCD.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pusan National University Yangsan Hospital
• Treatments: Dexmedetomidine; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• ≥ 60 years old, scheduled for laparoscopic cholecystectomy under general anesthesia

Exclusion Criteria:

• diseases of the central nervous system, including dementia (Mini Mental Examination Score <24),

• consumption of major tranquilizers or antidepressants

• previous neuropsychological testing

• the patient's inability to comply and follow procedures or poor comprehension of the language used in the study.

• Parkinson's disease

• Patients with a severe visual or auditory handicap, illiteracy

• alcoholism (intake of >5 units of alcohol daily during the last 3 months)

• drug dependence

• those not expected to complete the postoperative tests were excluded as well