Long-Term Growth and Skeletal Effects of Early Growth Hormone Treatment in Turner Syndrome
Status:
Completed
Trial end date:
2015-09-01
Target enrollment:
Participant gender:
Summary
This is an extension study that will gather long-term data on the effect of early growth
hormone (GH) treatment on adult height and other aspects of health and development in girls
with Turner syndrome. The main purpose is to determine whether girls who received 2 years of
GH treatment before 6 years of age achieve taller adult height than girls who were untreated
during this time. The study will also look at middle ear and hearing function, and cognitive
and behavioral development. Protocol completion is defined as attainment of height velocity
less than or equal to 1.0 cm/year, or bone age greater than or equal to 15 years.