Overview

Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2)

Status:
Active, not recruiting
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
The main aim of this clinical trial is to find a way of giving ch14.18/CHO, in combination with subcutaneous aldesleukin (IL-2) and oral isotretinoin (13-cis-RA), to children and young people with primary refractory or relapsed neuroblastoma without intravenous morphine.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
St. Anna Kinderkrebsforschung
Collaborators:
Alder Hey Children's NHS Foundation Trust
Centre Leon Berard
Children's University Hospital, Ireland
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Great Ormond Street Hospital for Children NHS Foundation Trust
Gustave Roussy, Cancer Campus, Grand Paris
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
Hospital Universitario La Fe
Institut Curie
Istituto Giannina Gaslini
Jena University Hospital
Johann Wolfgang Goethe University Hospital
Medical University Innsbruck
Medical University of Graz
Newcastle-upon-Tyne Hospitals NHS Trust
NHS Greater Glasgow and Clyde
Schneider Children's Medical Center, Israel
St. Anna Children's Hospital, Vienna
The Leeds Teaching Hospitals NHS Trust
University Hospital Southampton NHS Foundation Trust
University Hospital Tuebingen
University Hospital, Toulouse
University Hospitals Bristol and Weston NHS Foundation Trust
University Medicine Greifswald
Treatments:
Aldesleukin
Antibodies, Monoclonal
Dinutuximab
Interleukin-2
Isotretinoin