Overview

Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

Status:
Recruiting
Trial end date:
2023-01-30
Target enrollment:
Participant gender:
Summary
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete spinal cord injury. The investigators hypothesize that LT+TRT treatment will improve muscle size, muscle function, bone mineral density, and walking speed.
Phase:
Phase 2
Details
Lead Sponsor:
North Florida Foundation for Research and Education
Collaborators:
Brooks Rehabilitation
North Florida/South Georgia Veterans Health System
University of Florida
Treatments:
Methyltestosterone
Testosterone
Testosterone 17 beta-cypionate
Testosterone enanthate
Testosterone undecanoate