Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy.

• Status: Completed
• Trial end date: 2015-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this clinical study is to asses the effect of ultrasonic periodontal debridement associated to locally delivered doxycycline (20%) by PLGA microspheres on chronic generalized periodontitis treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Campinas, Brazil
• Treatments: Doxycycline

Criteria

Inclusion Criteria:

• Chronic generalized periodontitis (AAP,1999);

• At least 7 sites with probing depths >5mm, and 2 sites with probing depth >7mm;

• At least 20 teeth present;

• Systemically healthy.

Exclusion Criteria:

• Had received periodontal care 6 months prior to the study;

• Had taken medications known to interfere with periodontal health and healing 6 months prior to the study;

• Pregnants or lactants;

• Smokers;

• Sensitive to doxycycline.