Overview

Local Pilocarpine for Relieving Dry Mouth

Status:
Completed
Trial end date:
2020-01-31
Target enrollment:
Participant gender:
Summary
The investigators intended for this study to deliver the "proof-of-concept" that locally administered pilocarpine drops in two doses are effective in a population of elderly (aged ≥ 70 years) with xerostomia at the expense of limited adverse events. To this end, the study aims to quantify the effect size of pilocarpine in two different dosages. In case the investigators observe clinically meaningful changes in xerostomia through measured NRS, a sufficiently-powered RCT will be prepared to compare pilocarpine to placebo.
Phase:
Early Phase 1
Details
Lead Sponsor:
Maastricht University Medical Center
Treatments:
Ophthalmic Solutions
Pilocarpine