Overview

Local Minocycline to Reduce Future Inflammation and Bone Loss in Periodontal Maintenance Patients

Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to determine the effect of local application of minocycline microspheres on the periodontal inflammation and bone loss prevention in patients diagnosed with moderate-severe chronic periodontitis within a periodontal maintenance program.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Nebraska
Treatments:
Minocycline
Criteria
Inclusion Criteria:

- diagnosis of moderate-severe chronic periodontitis

- attending regular periodontal maintenance visits at UNMC COD

- one quadrant with at least one > 5 mm interproximal pocket and 3 posterior teeth

Exclusion Criteria:

- systemic diseases which impact periodontal inflammation and bone turnover

- drugs which significantly impact periodontal inflammation and bone turnover

- surgical periodontal therapy within the last year

- pregnant or breast-feeding females