Local Infiltration With Bupivacaine to Increase Quality of Post-operative Pain Control in Total Knee Replacement

• Status: Completed
• Trial end date: 2010-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy of periarticular injection with 0.25% bupivacaine for controlling pain after total knee replacement to improve the quality of post-operative care.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Collaborator: Siriraj Hospital
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• primary osteoarthritis patients undergoing total knee replacement at Siriraj Hospital

• BMI between 20-35

• having a full understanding of the question in this trial

Exclusion Criteria:

• allergy to NSAIDs, Acetaminophen, Bupivacaine

• blood creatinine more than 1.5 mg/dl or creatinine clearance less than 60 mL/min

• abnormal liver function

• previous surgery on the knee undergoing total knee replacement

• patient could not receive spinal anesthesia