Local Continuous Wound Infusion of Anesthetics in the Management of Post-operative Pain After Total Hip Arthroplasty.

• Status: Terminated
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The combination of subarachnoid anaesthesia (SAB) and continuous local wound infiltration (LCWI) with a consistent amount of local anaesthetics could prevent central sensitization through an additive or synergistic effect because it can maintain continuous inhibition of nociceptive afferents

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: San Salvatore Hospital of L'Aquila
• Treatments: Anesthetics; Bupivacaine; Levobupivacaine

Criteria

Inclusion Criteria:

• 18-90 years of age

• American Society of Anaesthesiologists (ASA) physical status I-III

• total hip arthroplasty.

Exclusion Criteria:

• pregnancy

• body mass index (BMI) >35

• allergy to local anaesthetics

• skeletal and/or muscle abnormalities of the spine

• primary and/or secondary neurological diseases

• psychiatric diseases

• history of chronic pain and/or neuropathic disorders

• history of drug abuse

• state of sepsis

• infection and/or tumours within the skin on the back

• primary or secondary coagulopathies

• primary or secondary heart, liver and renal failure.