Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery

• Status: Completed
• Trial end date: 2008-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the present study is to evaluate a new technique for prevention of sternal wound infection consisting of local application of collagen-gentamicin in addition to routine i.v. antibiotic prophylaxis.

The technique has been evaluated in a previous randomised study. The aim of the present study is to evaluate the technique after it has been introduced in clinical practise to monitor the bacterial antibiotic susceptibility and to verify that the suggested reduction in sternal wound infection still exits.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Region Örebro County
• Collaborator: University Hospital, Linkoeping
• Treatments: Gentamicins

Criteria

Inclusion Criteria:

• All consecutive cardiac surgery patients operated via median sternotomy

Exclusion Criteria:

• Existing inclusion of the patient in another study of treatment aimed at reducing postoperative SWI.

• Known allergy or other contraindication to gentamicin or bovine collagen.

• Pregnancy or breast feeding

• Treatment with aminoglycosides during the last week