Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
Status:
Recruiting
Trial end date:
2025-01-01
Target enrollment:
Participant gender:
Summary
The purpose of the clinical study is to investigate whether the local delivery of
bisphosphonate as a surgical adjuvant can decrease the chance of a giant cell tumor of bone
coming back to the same location. The hypothesis is that the local administration of
bisphosphonate will decrease the rate of the tumor returning compared to traditional
aggressive surgical removal of the tumor.
Phase:
Phase 3
Details
Lead Sponsor:
St. Louis University
Collaborators:
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) Indiana University Johns Hopkins University McGill University Health Centre/Research Institute of the McGill University Health Centre Medical College of Wisconsin Oregon Health and Science University Orthopaedic Research and Education Foundation The Cleveland Clinic University of California, Los Angeles University of Iowa University of Kansas University of Oklahoma Wake Forest University