Liver Positron Emission Tomography (PET) Study of Non Alcoholic Fatty Liver Disease

• Status: Completed
• Trial end date: 2011-01-19
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to evaluate how the liver receives and uses fats for energy. This will help the investigators further understand the physical and chemical processes responsible for Non-Alcoholic Fatty Liver Disease (NAFLD) in overweight females with or without NAFLD who are scheduled to undergo gastric bypass surgery.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Collaborator: Barnes-Jewish Hospital
• Treatments: Radiopharmaceuticals

Criteria

Inclusion Criteria:

• Obese females with a BMI of greater then or equal to 45.

• Age range between 18-45 years.

• Patients undergoing bariatric surgery at Barnes-Jewish Hospital-St.Louis,MO.

Exclusion Criteria:

• Any prior history or evidence of liver disease other than Non-Alcoholic Fatty liver Disease, severe hypertriglyceridemia and diabetes mellitis.

• Consumed greater then or equal to 20 grams of alcohol per day.

• Taking medications that are known to cause hepatic steatosis & liver damage.