Overview

Liposomal Doxorubicin and Estramustine Phosphate: Study in Taxane Resistant, Hormone Refractory Advanced Prostate Cancer

Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to test the safety, tolerability, and effectiveness of the drug combination of Doxil (doxorubicin) and estramustine when used to treat prostate cancer that is resistant to hormones and to a chemotherapy type called taxanes. The primary hypothesis is to reduce the measurable disease or prostate-specific antigen (PSA) level by at least 50% from baseline.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Morton Plant Mease Health Care
Collaborator:
Ortho Biotech Products, L.P.
Treatments:
Doxorubicin
Estramustine
Hormones
Liposomal doxorubicin
Taxane