The aim of this study is to compare the effects of preemptive analgesia using liposomal
bupivacaine mixed with bupivacaine HCl, versus bupivacaine HCl alone for uterosacral ligament
injection in patients undergoing vaginal hysterectomy. We hypothesize that the group
receiving a combination of liposomal bupivacaine and bupivacaine HCl will report superior
postoperative pain management. Enhancement in pain control should confer a decrease in opioid
and other analgesic medication requirements, which may contribute to decreased nausea,
vomiting, and higher overall patient satisfaction with pain control.