Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients
Status:
Recruiting
Trial end date:
2025-01-01
Target enrollment:
Participant gender:
Summary
Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce
more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within
liposomes, which break down in soft tissue over time. Typical length of therapeutic effect
for standard bupivacaine is up to 6 hours. The liposomal formulation of bupivacaine, however,
has a length of therapeutic effect of up to 72 hours. Typical post-operative incisional pain
is known to last for several days in most cases and is thought to peak between 1-2 days after
surgery. Therefore, the benefit of most short-acting local analgesics does not overlap with
the period of most need.