Lipid Lowering Agents to Limit Lipid Oxidation and Activation of Clotting System in Nephrotic Syndrome
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to learn if using statin in patients with nephrotic
syndrome could lower the risk of blood clots. Nephrotic syndrome is a collection of signs and
symptoms that occur when the glomeruli -the tiny filters that work in the kidney- leak
protein in the urine.
One of the symptoms associated with nephrotic syndrome is hyperlipidemia: too much bad
cholesterol (LDL). This bad cholesterol could be linked to the increased risk of blood clots
in patients with nephrotic syndrome. The study doctors would like to see if taking a statin
drug to reduce the amount of bad cholesterol could reduce the risk of blood clots.
Phase:
Phase 1
Details
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)