Overview

Linezolid Pharmacokinetics (PK) in Multi-Drug Resistant (MDR)/Extensively-Drug Resistant (XDR) Tuberculosis (TB)

Status:
Completed
Trial end date:
2010-05-01
Target enrollment:
Participant gender:
Summary
This is a one-period, double-blind, single-center pharmacokinetic study of linezolid in patients with MDR or XDR tuberculosis treated with linezolid and an Optimized Background Therapy (defined as treatment with > 4 drugs with activity against tuberculosis to which the patient's isolate is believed to be sensitive by history or based on drug sensitivity testing).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Centers for Disease Control and Prevention
Collaborators:
Boston University
Columbia University
Pfizer
University of Cape Town
University of KwaZulu
University of Texas
Treatments:
Linezolid